Evolution Of Biological Nanomachines? (part 1)

As we zoom in the lense to close exermine life, the wonders never end. According to modern knowledge of cell biology, what Dawrin thought the cell was is, if one may be very kind, hillarius. This was the guy who was fond of saying 'simple things' blindly evolved to 'complex things'. Ultimately then, everything came from a single cell. Was he confusing 'small' with 'simple'. A wrist watch can be more ingeniously made than as system of wrist watches each of which is taken as a black box. It is fractal complexity where the parts are as complex as the whole. Compare it with an hologram where breaking it into pieces does not create small parts but rather, small wholes.Modern scientist can be very hand wavy when he describes complex things to leymen. The common description of leaving things are often on the same par with describing a car as piston, moved by expanding fuel, which then drives the shaft, which then drives the wheels. Of course if you have such a non picture of a car in your mind, you will find it easy to accept an equivalent hand wave of how it might have evolved through pure accidents. You know, it all begun with pushing heavy objects. Then we begun to use logs as wheels, then the wooden wheel evolved in Mesopotamia. Then perharps in some road accident, the wheel was converted to a bisycle type wheel. Wink wink nudge nudge the mind bogling vehicle in the road evolved!It is not at all bad if such careless sweep through a complex matter prepares one to search farther. But problems comes when the bozos ends up confusing themselves as well. So you find them thinking of genetically modifying leaving things!! Thats funny! Boys who are yet to understand how a bicycle works trying to modify a nuclear submarine? When the leymen on the other hand say 'scientist know it' yet they themselves have no clue, then there is no difference between modern science with any other priesthood.The problem with Dawrin's evolution is pretty straight foward even to the extend that a child can understand it. But thanks to the confusing smart scientist. One still has to unwind it with pages and pages. The gist of the matter in summary is that: given an already functioning thing, trying to modify it blindly will most certainly rather spoils it. This is because you will thus have to tamper with the things that were already working.LET NOT DAWRIN UNWITTINGLY DENY HIS OWN DOCTRINEThese biological machinery is built from the blue print of DNA. That is where it is worse to tamper with. To introduce a new working gene in the DNA, we must be carefull not to thus destroy another already working gene. An example will help. Lets say the gene encoding Insulin starts somewhere and ends somewhere. From where it ends, a gene encording ATP synthase begines. To insert our new gene savely, we must put it at the exact middle so it damages neither of the other genes by spliting them apart.The biological nanomachines are not simple. They are composed of many parts working together. Non of which can work without the other! Questions arises as to how the parts were naturaly selected before the other parts came into existence. A Dawrin then may be forced to say that gene A, which codes part X came into being but it could still remain if protein X is not harmfull to the cell. But we have seen that we must insert A precisely in between two working genes. Up until other parts that are supposed to work with A comes into being, a series of accidents must happen in between A and the other two genes! So it becomes a DNA black spot! An accident happening such that it splits say insulin, that gene is selected against. But then if an accident splits A, then nothing happens since after all A is yet to serve any important purpose. So for the whole set of genes working together with A to evolve, accidents must happen only near A yet there is no Dawrinian reason yet as to why A should be selected!! Accidents somehow constrained to happen at only one point along the road are not accidents at all. They are planned! It seems more sensible to say that A is selected for what it WILL do in future and not what it HAS done in past! It is still a teleological evolution.TYPE 3 SECRETION SYSTEM (TTSS) AND FLAGELLUMLet us take a tour to some two nanomachines in nature that each have parts that work together in a remarkable way. I use this because when you ask a Dawrinian where the flagellum came from, he says that it evolved from TTSS and when you ask where TTSS came from, he says it evolved from flagellum! Otherwise ALL biological machines are such ingenious. Nothing at all is peculiar about the flagellum.The flagellum is an electrostatic motor with a drum like rotor connected to a rod that acts as an axle. This rod then drives a whiplike structure that then enables the bacteria to swim like a motor boat!The stator together with the rod looks exactly like an automatic shringe found in the bacteria. So might one had simply morphed accidentally into the other? Lets pull out our binoculous very well. The motor has bearings termed L-ring and S-rings attatched to the outer membrane. The shringe has perfectly similar rings. However, when we close exermine the details of the proteins making the shringe, they differ remarkably from those of the motor. Specifically in the former they are bonded to the rod (which acts as a needle in this case). Then they are pumbs and not just securing pegs! So we have a rivet vs a wheel, functionaly, they are miles apart.So the rings making the outer part of the shringe must be entirely replaced before the motor can even begine to rotate! Even a single protein binding the rod will make the entire motor useless! So the shape similarity between the rings serve absolutely no purpose in making the shift from shringe to motor easy. Farthermore, the rings are made by joining 40 or so identical proteins. Each protein inturn should have hundreds of amino acids arranged in precise ways. So how will these replacings happen like accidents! If they happen one at a time, it will look just like a case of someone bringing bricks slowly, preparing to build a house. What selects the bricks is a usefull 'house' that is yet to be build! No natural selection yet because the motor that is being build is milleniums ahead! If anything such replacements should easier be selected against because, it in the proces, removes the proteins that were acting as pumb in the shringe!Now, lets close exermine the rod. The rod is not build from the same proteins as the needle! So again, what is similar is just the shape! So let us get it clear: are the bozos saying that if there are plastic shringes around, a similarly shaped yet metalic ones will easily evolve from the plastic shringes? Of course you know that the latter needs an entirely different factory.At the inner membrane, the motor has a drum like structure termed MS-ring. Needless to say, the outer part of the motor is not the same as that of the shringe. Even if it were the same, it would even be more amazing. Why should accidents make a pump using a rather complex stator of a motor? That would be like building a house using the body of a car!It might be tempting to think that it begun with a poor motor then Dawrin selected the better ones. When we think more carefully, this collapses in picoseconds! A simply waging flagellum will not only serve no purpose to the bacteria, it would be dangerous. A motor must have a full control before it can be SAVE, let alone serve any use. Without control, the flagellum will drive the bacteria any howly, even to dangerous places. If you have a fully functioning car without a mere stearing wheel, such a car will just not be worthless, it will be dangerous. Such cars lacking stearing wheels will be selected against milleniums before accident #200000000 create a stearing wheel, no matter how complex they are! Cars must also have breaks.This blog is to be continued in the next blog...

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Evolution Of Biological Nanomachines? (part 1)

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